Expression of chemokine-like factor 2 (CKLF?2) mRNA in rat myocardium at different development phase
- VernacularTitle:趋化素样因子2(CKLF2)mRNA在不同发育期大鼠心肌中的表达
- Author:
Hongkun REN
;
Tao HONG
;
Jie JIANG
- Publication Type:Journal Article
- Keywords:
Chemokines;
Myocardium;
Rats
- From:
Chinese Journal of Interventional Cardiology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of CKLF?2 mRNA in rats′ myocardium at different development phase. Methods Total RNA was extracted from fetal rat hearts at day12 and day 18 after coitus, and from new-born rat hearts right after birth, day 3, day 7 and day 21 after birth, as well as from adult rat hearts. The expression of CKLF?2 mRNA was tested by competitive polymerase chain reaction (CPCR). Results Compared with the postnatal myocardium, the expression of CKLF?2 mRNA obtained its peak level in the 12-day-post coitus, which then decreased gradually to a relatively low level until birth. It increased slightly at birth and subsided to the lowest level in adulthood. Conclusion CKLF?2 probably takes part in the procession of the myocardial proliferation and the development of rat′s heart.
