Correlation of striatum dopamine transporter imaging and the scores of Parkinsonian clinical scale in patients with Parkinson's disease
- VernacularTitle:帕金森病患者纹状体多巴胺转运体显像与帕金森病临床量表评分的相关性
- Author:
Qing DONG
;
Jianping LI
;
Jianjun LIU
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
dopamine transporter;
SPECT;
UPDRS
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the correlation of striatum dopamine transporter (DAT) imaging and the scores of Parkinsonian clinical scale in patients with Parkinson's disease(PD).Methods 99m Tc-TRODAT-1 SPECT imaging was used to assess the DAT binding in the striatums of 29 PD patients, their correlations with the subscales of unified PD rating scale (UPDRS), age and disease duration were also evaluated.Results The scores of subscales of UPDRS II, III and V, as well as the disease duration were negatively correlated with DAT bindings in ipsi-, contra- and bilateral striatum regions (r was -0.70, -0.80, -0.49 and -0.54 respectively, all P
