Effect of deep brain stimulation of subthalamic nucleus on anxiety and depression of patients with Parkinson's disease
- VernacularTitle:丘脑底核深部电刺激对帕金森病患者抑郁及焦虑的影响
- Author:
Qiaoshu WANG
;
Yongbo ZHAO
;
Bomin SUN
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
deep brain stimulation;
subthalamic nucleus;
depression;
anxiety
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of bilateral subthalamic nuclei deep brain stimulation (STN-DBS) on anxiety and depression of patients with Parkinson's disease(PD).Methods Forty-one consecutive patients with refractory motor fluctuations and dyskinesia were assessed with Hoehn & Yahr scale, Unified Parkinson’s Disease Rating Scale Ⅲ (UPDRSⅢ), HADS, PD Questionnaire Chinese version (PDQ-39) a week before surgery and 12 months after the surgical procedure. Results The scores of UPDRSⅢ, HADS and PDQ-39 significantly increased after STN-DBS treatment (all P
