Effect of local mild hypothermia therapy on stress hormones in patients with acute cerebral hemorrhage
- VernacularTitle:局部亚低温治疗对急性脑出血患者应激激素的影响
- Author:
Xueping LIU
;
Xiuzhou ZHANG
;
Minzhong WANG
- Publication Type:Journal Article
- Keywords:
local mild hypothermia;
cerebral hemorrhage;
stress hormone
- From:
Journal of Clinical Neurology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of local mild hypothermia on stress hormones in patients with acute cerebral hemorrhage.Methods 78 patients were randomly divided into two groups, mild hypothermia group (38 cases) and routine group (40 cases). Conventional treatment was used in both groups, and local mild hypothermia therapy was applied in mild hypothermia group. The concentrations of corticotropin-releasing hormone (CRH), adrenocorticotropic hormone (ACTH), corticosteroid (CS) and aldosterone (ALD) in plasma pretherapy and at 3rd, 7th day after treatment were measured. The scores of clinical neurological deficit prior and at 3rd week after treatment were observed.Results The levels of plasma ACTH, CRH, CS and ALD prior treatment both in mild hypothermia and routine group were higher than those in healthy control group (all P