Progress on tumor angiogenesis and gene therapy for antiangiogenesis
- VernacularTitle:肿瘤血管生成与抗肿瘤血管生成基因治疗的进展
- Author:
Xiaoping HE
;
Renmin ZHU
- Publication Type:Journal Article
- Keywords:
Angiogenesis;
Gene therapy;
Tumor
- From:
Journal of Medical Postgraduates
2003;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Tumor angiogenesis, resulting from the imbalance of angiogenic cytokines and angiogenesis inhibitors, is crucial for tumor growth and metastasis. As a new field of cancer therapy, tumor anti-angiogenesis therapy with regard to abrogation of tumor vasculature has become an important anti-tumor strategy. Gene therapies have the potential to provide antiangiogenic mediators specifically targeted to organs containing tumors and make a great improvement in this therapy. This article reviews the current understanding of tumor angiogenesis, with a focus on gene therapy in this field.
