Helping to early diagnosis of SARS by flow cytometric three color absolute count of T lymphocyte subsets in blood
- VernacularTitle:流式细胞术三色绝对计数T淋巴细胞亚群对传染性非典型肺炎早期诊断的意义
- Author:
Jiaying YUAN
;
Jianzhong WANG
;
Run WANG
;
Yanjun ZHAO
;
Aiyu ZHANG
- Publication Type:Journal Article
- Keywords:
Severe acute respiratory syndrome;
T- lymphocyte subsets;
Flow cytometry
- From:
Chinese Journal of Laboratory Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the changes of T lymphocyte subsets of severe acute respiratory syndrome(SARS) patients during acute phase and recovery stage and study its clinical significance in early diagnosis of SARS.Methods T lymphocyte subsets of 40 patients of SARS and 22 cases of SARS recovery stage were detected by flow cytometry.Results Compared with normal group, T lymphocyte, Th and Ts cell counts of SARS patients decreased obviously( P =0.013, P 0.05). Conclusion The cellular immunity of SARS patients were badly damaged during acute phase. Their T lymphocyte, Th and Ts cell counts decreased obviously. This could be a guideline of early diagnosis of SARS. The counts of T lymphocyte subsets of SARS patients can return to normal after they were cured.
