Clinical applications of angiotensin Ⅱ receptor blockers in IgA nephropathy
- VernacularTitle:血管紧张素Ⅱ受体拮抗剂在IgA肾病中的临床应用
- Author:
Zhengkun XIA
- Publication Type:Journal Article
- Keywords:
Angiotensin Ⅱ receptor blockers;
IgA nephropathy;
Proteinuria
- From:
Journal of Medical Postgraduates
2003;0(05):-
- CountryChina
- Language:Chinese
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Abstract:
Angiotensin Ⅱ receptor blockers(ARB) are recently studied as renin-angiotensin system (RAS) inhibitors. They were firstly used in hypertension therapy, while now are widely administered to reduce urinary protein and slow the progression of proteinuric nephropathy to end-stage renal failure in nephropathy treatment. They are considered effective in IgA nephropathy according to its character. This review briefly discusses the mechanism, function, and tissue distribution of ARBs, and the corresponding advances in IgAN treatment.