A Case of Vasospastic Angina Pectoris Occurring Following Administration of Oral Imigran(R) for Migraine.
10.4070/kcj.2001.31.10.1071
- Author:
Ki Hyun CHOI
1
;
Tae Yong KIM
;
Jae Hyuk CHOI
;
Jae Wook OK
;
Jin Chan PARK
;
Jane OH
;
Yoon Kyung CHO
;
Kyung Hwa HWANG
;
Sang Wook LIM
;
Dong Hoon CHA
Author Information
1. Division of Cardiology, Department of Internal Medicine, Pundang CHA Hospital, Pochon Joongmoon Medical College, Sungnam, Korea.
- Publication Type:Case Report
- Keywords:
Sumatriptan;
Migraine;
Angina pectoris;
variant
- MeSH:
Angina Pectoris*;
Cluster Headache;
Humans;
Migraine Disorders*;
Nitroglycerin;
Serotonin;
Sumatriptan;
Thorax;
Vasoconstriction
- From:Korean Circulation Journal
2001;31(10):1071-1074
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Imigran(R) (sumatriptan), a 5-hydroxytryptamine (HT) derivative, is highly effective in aborting attacks of migraine and cluster headache. The drug is generally well tolerated. However tolerated, although up to 8% of patients consistently have demonstrate chest symptoms, including chest pressure, tightness, and pain, often mimicking angina pectoris. It has been suggested that these chest symptoms are caused by coronary vasoconstriction, and that this effect may be mediated by endothelial dysfunction. This can be reversed by the administration of glyceryl trinitrate. We report a case of vasospastic angina pectoris occurring after the administration of oral sumatriptan in a patient with migraine.
