The current progress of uncoupling protein 2 in myocardial energy metabolism
- VernacularTitle:解耦联蛋白2的生理特性及其在心肌能量代谢中研究进展
- Author:
Zhaoqi HUANG
;
Shisen JIANG
- Publication Type:Journal Article
- Keywords:
Uncoupling protein 2;
Myocardial mitochondrion;
Myocardial energy metabolism
- From:
Journal of Medical Postgraduates
2003;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Uncoupling protein 2 (UCP2), a member of the mitochondrial inner membrane carrier family, partly dissipate the proton electrochemical gradient, decrease ATP production. UCP2 limits production of reactive oxygen species (ROS) and inhibits insulin secretion and regulates fatty acid oxidation. FFA, PPAR?,leptin, thyroid hormones and so on could regulate the UCP2 expression. The function of UCP2 in myocardial energy metabolism remains unknown.
