The study of biocompatibility of polyurethane sponges made in China
- VernacularTitle:评价几种国产聚氨酯海绵的生物相容性
- Author:
Rui WANG
;
Shaozong CHEN
;
Xueyong LI
;
Longshun XU
;
Wangzhou LI
- Publication Type:Journal Article
- Keywords:
polyurethane;
extract liquid;
cytotoxicity test;
colorimetry;
biocompatibility;
sensitization
- From:
Chinese Medical Equipment Journal
1993;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the biocompatibility of four kinds of polyurethane sponges made in China. Methods According to ASTM Standards for Medical Devices of America, polyurethane sponges are used to perform such biological tests as cytotoxicity test, acute toxicity test, pyrogenic reactions test, stimulation test of conjunctiva and cornea, sensitization test. The data are analyzed and evaluated according to the criterion. Results Reaction scales of these polyurethane sponges in cytotoxicity are 0 or 1 level. No toxicity effects and pyrogenic reactions are observed in vivo test. No conjunctiva and cornea irritation reactions and no sensitization reactions are found. Conclusions The four kinds of polyurethane sponges have high biocompatibility and can become ideal dressings of Vacuum-Assisted Closure.
