Expression and its significance of MyT1 in the brain of epileptic rats induced by lithium chloride -pilocarpine
- VernacularTitle:氯化锂-匹罗卡品致大鼠脑髓鞘转录因子的表达及其意义
- Author:
Huajie LI
;
Shiyao BAO
;
Yuan XU
- Publication Type:Journal Article
- Keywords:
epilepsy;
myelin transcription factor 1;
lithium chloride;
pilocarpine
- From:
Journal of Clinical Neurology
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of myelin transcription factor 1 (MyT1) and its significance in the brain of epileptic rats induced by lithium chloride-pilocarpine. Methods Models of epilepsy of SD rats were established by intraperitoneal injection with lithium chloride and pilocarpine. MyT1-positive cells in the cortex and hippocampal field CA 1 of epileptic rats were determined by immunofluorescence histochemistry.Results Compared with the control group, the number of MyT1-positive cells within the cortex and hippocampal field CA 1 of epileptic rats decreased significantly at 1 day after seizure ( P
