Comparison of Efficacy between Paroxetine and Estazolam on Chronic Insomnia
- VernacularTitle:帕罗西汀治疗慢性失眠症的临床对照研究
- Author:
Jing XU
;
Junping WANG
;
Zhiyun HU
- Publication Type:Journal Article
- Keywords:
Clinical psychology chronic insomnia case control studies
- From:
Chinese Mental Health Journal
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determine whether paroxetine would be effective in the treatment of patients with chronic insomnia and to compare efficacy of paroxetine and estazolam on chronic insomnia. Methods: 74 patients with chronic insomnia were divided into 2 groups, receiving treatments of paroxetine and estazolam respectively. All of the subjects were assessed with Pittsburgh Sleep Quality Index (PSQI) and sleep diary. Results: 1. On the eighth day of treatment, estazolam group showed improvement, all the indexes of sleep were better than those before treatment and those of paroxetine group; 2. On the fifteenth day of treatment, paroxetine group showed improvement, all the indexes of sleep were better than those before treatment and those of estazolam group, while the indexes of the estazolam group returned to pre-treatment level. 3. At the end of treatments and 3 months' follow up, paroxetine group still showed better effect in sleep indexes than estazolam group and the pre-treatment level. Conclusion: paroxetine is effective in the treatment of chronic insomnia and shows long-term effect.
