Progress in studies on interleukin-12 inhibiting angiogenensis of tumor
- VernacularTitle:白细胞介素-12抑制肿瘤血管生成的研究进展
- Author:
Lin YAN
;
Yunlong PAN
- Publication Type:Journal Article
- Keywords:
Interleukin-12;
Inhibit;
Angiogenesis;
Tumor
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-12 can induce the production of INF-?, up-regulate the inhibitive factor of angiogenesis such as IP-10, MIG, TIMP, TNF-?, down-regulate the induced factor of angiogenesis such as VEGF, bFGF, MMP, inhibit the angiogenesis of tumor together and accelerate the regression of tumor. Interleukin-12 can inhibit the angiogenesis of tumor, which is independent of the immune system.
