Effects of Endurance Training and Chinese Medicine Compound for Invigorating Qi and Tonifying the Kidney on Testicular StAR and P450_(SCC) mRNA Levels in Rats
- VernacularTitle:耐力训练和益气补肾中药对睾酮合成的调节因素——StAR蛋白和P450_(SCC)酶mRNA表达的影响
- Author:
Qirong WANG
;
Lili ZHOU
;
Shicheng LI
- Publication Type:Journal Article
- Keywords:
endurance training,Chinese medicine,testosterone,StAR,P450 SCC,RT-PCR$$$$
- From:
Chinese Journal of Sports Medicine
1982;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective Effects of exercise training and Chinese Medicine Compound for Invigorating Qi and Tonifying the Kidney on testicular StAR and P450 SCC mRNA expression in rats were observed. Methods 50 Wistar rats were randomly divided into 4 groups: sedentary control group(SC, n=10), sedentary with medicine group (SM,n=10), training group(T, n=15) and training with medicine group(TM, n=15). After 6 weeks swimming training , serum testosterone level of rats were tested through radioimmunological method; using RT-PCR, we measured testicular StAR and P450 SCC mRNA levels of rats. Results (1) In T group, serum testosterone level was lower than that in SM and TM groups. Whereas, compared with SC group, the serum testosterone level in TM group kept steadiness. (2) In T group, the gene expression of StAR was markedly lower than that in SC control (P