Changes and clinical significance of P selectin , lysosome protein expression in patients with ischemic stroke
- VernacularTitle:缺血性脑卒中患者P选择素、溶酶体蛋白表达的变化及其临床意义
- Author:
Yongmei SHI
;
Hong ZHOU
- Publication Type:Journal Article
- Keywords:
ischemic stroke;
CD 62P;
CD 63;
flow cytometry
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the changes and clinical significance of P selectin (CD 62P), lysosome protein (CD 63) expression in patients with ischemic stroke.Methods 168 cases of acute ischemic stroke (both acute and convalescence) and 40 normal controls were tested for CD 62P and CD 63 expression using flow cytometry. The correlation between the expression and neurological functional deficit scale was analyzed.Results (1) The expression of CD 62p and CD 63 in acute phase (9.48%, 8.36%) of ischemic stroke was markedly higher than that in convalescence phase (5.73%, 4.21%)( P0.05). (3) CD 62P and CD 63 expressions were positively related with the scores of neurological functional deficit scale( r=0.84 and r=0.817, P
