Study of the relationship between polymorphism of angiotensin converting enzyme gene and vascular dementia
- VernacularTitle:血管紧张素转换酶基因多态性与血管性痴呆发病关系的研究
- Author:
Hong LIU
;
Wenqing ZHANG
- Publication Type:Journal Article
- Keywords:
vascular dementia;
angiotensin converting enzyme;
gene polymorphism
- From:
Journal of Clinical Neurology
1992;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between polymorphism of angiotensin converting enzyme (ACE) gene and vascular dementia (VD).Methods 94 cases of VD, 60 cases of essential hypertension (EH) and 60 healthy controls were enrolled to analyze insertion/deletion polymorphism of ACE gene by polymerase chain reaction (PCR).Results The DD genotype and the frequency of D allele were significantly higher in VD patients than in healthy controls (all P
