Clinical safety of statins
- VernacularTitle:他汀类药物临床应用的安全性
- Author:
Xiaowei YAN
- Publication Type:Journal Article
- Keywords:
statins;
LDL cholesterol;
safety profile;
myopathy
- From:
Basic & Clinical Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Accumulated clinical trials have demonstrated the clinical efficacy of statins,which is closely associated with the magnitude of LDL-C reduction,in primary and secondary prevention of cardiovascular diseases.The concept of intensive LDL-C lowing has been widely accepted.Although statins are classified as a group of drugs with documented safety and tolerability,the potential risk profile in liver and skeleton muscle under the intensive treatment with large dose has drawn great attention.
