A Large Intrathoracic Meningocele in a Patient with Neurofibromatosis-1.
10.3904/kjim.2010.25.2.221
- Author:
Jae Wook JEONG
1
;
Kwang Young PARK
;
Sang Min YOON
;
Du Whan CHOE
;
Cheol Hyeon KIM
;
Jae Cheol LEE
Author Information
1. Department of Internal Medicine, Korea Cancer Center Hospital, Seoul, Korea. jclee@kcch.re.kr
- Publication Type:Case Report ; Review
- Keywords:
Meningocele;
Neurofibromatosis 1
- MeSH:
Adult;
Diagnosis, Differential;
Female;
Humans;
Incidental Findings;
Meningocele/*complications/*pathology;
Neurofibromatosis 1/*complications/genetics/*pathology;
Pedigree
- From:The Korean Journal of Internal Medicine
2010;25(2):221-223
- CountryRepublic of Korea
- Language:English
-
Abstract:
A large intrathoracic meningocele, a saccular protrusion of the meninges through a dilated intervertebral foramen or a bony defect of the vertebral column, was diagnosed in a 41-year-old female patient showing clinical features of neurofibromatosis-1 (NF-1), including cafe-au-lait spots, cutaneous neurofibromas, and axillary frecklings and Lisch nodules on the iris. Her daughter and son also had similar manifestations of NF-1. Regular follow-up with periodic imaging was recommended without surgical treatment because there were no signs or symptoms. Meningocele should be differentiated from posterior mediastinal tumors such as neurofibroma, neuroblastoma, and ganglioneuroma because NF-1 has a high risk of tumor formation. We report on this case with a brief review of the literature.
