Gene chip and its use in the detection of mutations
- VernacularTitle:基因芯片及其在突变检测中的应用
- Author:
Jinheng LI
;
Bing CHEN
- Publication Type:Journal Article
- Keywords:
Gene chip;
Mutation detection;
Optimizing drug therapy
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Gene chip is an important biological technology, which is developing quickly recently. In this article, we reviewed the origin, development, basic operation of gene chip. Several kinds of gene chips including tiled array, direct allele specific fluorescence targeting (DAFT) array, labeled auxiliary oligonucleotides array, ligase detection reaction array, and peptide nucleic acid array were introduced as examples for their use in mutation detection. The prospect of the use of gene chip in optimizing drug therapy was also discussed.
