Preparation of polysaccharides from Sargassum fusiforme and its inhibitory effect on the HepG_2 cell
- VernacularTitle:羊栖菜多糖的制备及其对HepG_2细胞的抑制作用
- Author:
Yingzhou CEN
;
Xiajun MA
;
Lingyun WANG
;
Shaoyu XU
;
Yifei WANG
;
Meiyin ZHANG
- Publication Type:Journal Article
- Keywords:
polysaccharide from Sargassum fusiforme;
antitumor effect;
HepG 2 cell;
isolation;
hydrolyzation
- From:
Chinese Journal of Marine Drugs
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the inhibitory effect of polysaccharides from Sargassum fusiforme on the HepG 2 cells. Methods Six kinds of polysaccharides were prepared by hot water extracting, ethanol and CaCl 2 precipitating and acid hydrolyzing. Inhibition rate of these polysaccharides on the HepG 2 cells were determined by MTT bioassay. Results Inhibition rate of two kinds of polysaccharides increased at lower concentration. Inhibition ratie of other polysaccharides increased with the increment of concentration. At the dose less than 2000mg?L -1,inhibition rate was not more than 40%. Conclusion All polysaccharide specimens obtained from Sargassum fusiforme have some inhibitory effects on human liver cancer cells HepG 2.
