Acute hypervolemic hemodilution for reducing perioperative blood use
- VernacularTitle:急性高容血液稀释减少围术期用血的可行性研究
- Author:
Xiangde ZHENG
;
Ying ZHANG
;
Qing FENG
- Publication Type:Journal Article
- Keywords:
Hemodilution;
Blood plasma substitute;
Blood loss;
Circulation;
Coagulation
- From:
Chinese Journal of Blood Transfusion
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the feasibility of preoperative acute hypervolemic hemodilution for decreasing perioperative blood use. Methods Thirty two patients(ASAI-II) undergoing spinal surgery were randomized into AHH group and control group. After anesthesia 6% HES(200/0.5) was given through internal jugular vein for AHH. The blood volume was increased by about 25%. During the operation, blood loss was replaced by HES in equal volume. Blood was transfused when the Hct dropped below 25%. The HR, MAP, CVP, SPO2, Hb, Hct., Plt, FIB, APTT, PT, amount of blood loss, blood transfused and urine output, volume of drainage 24h after operation and VAS score (0 means no effect, 10 means maximal effect) were observed before AHH, at the end of AHH, at the end of operation, and 24h after the operation. Blood volume expansion was calculated. Results (1) HR increased significantly in both groups(P
