Dynamic changes and their clinical significance of plasma ET, CGRP and ANP in elderly patients with acute cerebral infarction
- VernacularTitle:老年急性脑梗死患者血浆内皮素、降钙素基因相关肽、心钠素的动态变化及其临床意义
- Author:
Jing YU
;
Xueyuan LIU
;
Yujuan CHEN
- Publication Type:Journal Article
- Keywords:
acute cerebral infarction;
endothelin;
calcitonin gene related peptide;
trial natriuretic peptide
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the dynamic changes of plasma endothelin (ET), calcitonin gene related peptide (CGRP) and atial natriuretic peptide (ANP) in elderly patients with acute cerebral infarction and explore the pathological role of ET, CGRP and ANP in the development of acute cerebral infarction.Methods The concentrations of ET, CGRP and ANP in plasma were determined with radioimmunoassay in 78 elderly patients with acute cerebral infarction and 60 normal controls.Results (1)The levels of ET and ANP in patient group were significantly higher than those in control group ( P3 cm) and small area infarct group (1.5~3.0 cm) were significantly higher (all P