Experimental study on expression of transferrin in brain tissue after intracerebral hemorrhage in rats
- VernacularTitle:大鼠脑出血后脑组织转铁蛋白表达的实验研究
- Author:
Shaohua LIU
;
Yajun JIANG
;
Haoxin WU
- Publication Type:Journal Article
- Keywords:
intracerebral hemorrhage;
transferrin;
immunohistochemistry
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and its rule of transferrin (Tf) in brain tissue at different time after experimental intracerebral hemorrhage (ICH) in rats. Methods The fresh quantitative autologous blood was infused into the right caudate nucleus of rat sterotaxically to build up experimental ICH model. At 6h, 24h, 72h and 7d after operation, the rats were sacrificed and the brain tissues were made for immunohistochemistry analysis of Tf. The water content of the brains was also assayed.Results Compared with saline group, Tf-immunostaining positive cells in the tissue surrounding hematoma and in the ipsilateral pallium in ICH rats were increased significantly during 7 days, peaked at 72 hours ( P
