Experimental research of protective effect of Ischemia preadaptation to myocardium injury of ischemia reperfusion
- VernacularTitle:缺血预适应对心肌缺血-再灌注损伤保护效应的实验研究
- Author:
Chunjie LI
;
Hongxin CAO
;
Bolin YU
- Publication Type:Journal Article
- Keywords:
Myocardium ischemia;
Ischemia perconditioning;
Injury of ischemia reperfusion
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore research the protective effect of ischemia preconditioning to rabbits′myocardium injury of ischemia reperfusion, and discuss its mechanism. Methods: We randomly divide rabbits into 3 groups ( 8 rabbits every group ) , namely non-operation group . ischemia reperfusion group ( IR ) . ischemia preadaptation group ( IP ), and observed the level of enzymatic dynamics of myocardium,SOD,MDA, ET and correlation peptide of calcitonin gene. Results: In terms of the level of enzymatic dynamics of myocardium, SOD,MDA, ET and CGRP, the differences between IR and IP are very obviously (P
