Study on expression and relationship between MMP-9 and EGFR in NSCLC
- VernacularTitle:基质金属蛋白酶-9和表皮生长因子受体在非小细胞肺癌中的表达及相关性研究
- Author:
Xiaohui XU
;
Gen WANG
- Publication Type:Journal Article
- Keywords:
Matrix metalloproteinase-9;
Epidermal growth factor;
Receptor;
Non small cell lung cancer
- From:
Journal of Medical Postgraduates
2003;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the relationship and prognostic significance of matrix metalloproteinase-9(MMP-9)、epidermal growth factor receptor(EGFR) in patients with non- small cell lung cancer(NSCLC). Methods:Immunohistochemical method (S-P) was used to detect the expression of the MMP-9、EGFR in 62 NSCLC tissues and 18 normal lung tissues. Results:The positive expression rates of MMP-9 and EGFR were 67.7%,58.1% respectively in the 62 NSCLC.Their expression levels were significantly higher than those in 18 para-cancerous normal lung tissues(P
