Effect of laparoscopic cholecystectomy on systemic inflammatory immunological reactions
- VernacularTitle:腹腔镜胆囊切除术对机体炎症免疫反应的影响
- Author:
Yong WANG
;
Bingrong ZHANG
;
Qing WANG
- Publication Type:Journal Article
- Keywords:
Laparoscopic cholecystectomy;
Open cholecystectomy;
Immunological reaction;
T-lymphocyte
- From:
Chinese Journal of Minimally Invasive Surgery
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare laparoscopic cholecystectomy (LC) and open cholecystectomy (OC) on their effects on systemic inflammatory immunological reactions. Methods Peripheral T-lymphocyte subpopulation, white blood cell (WBC) count, C-reactive protein (CRP) and Interleukin-6 (IL-6) before the surgery, 1 hour, 1 day and 2 days after the surgery, respectively, in patients with cholelithiasis or polypoid lesions of the gallbladder receiving either LC (n=30) or OC (n=30), were recorded and compared. The enzyme-linked immunosorbent assay (ELISA) was used for IL-6 determination and the flow cytometry was adopted for T-lymphocyte subpopulation counting. Results The levels of CD3 ( q =5 822, P 0 05). Significantly lowered levels of WBC count ( t =4 904, P =0 000), CRP ( t =9 409, P =0 000) and IL-6 ( t =6 471, P =0 000) in group LC as compared with group OC 2 days after the surgery were observed. Conclusions LC imposes less influences on the systemic inflammatory immunological reactions and benefits the patient’s recovery.
