Changes of plasma adrenomedullin and expression of adrenomedullin and its receptor in villus of normal early pregnancy
- VernacularTitle:正常早期妊娠血浆和绒毛组织中肾上腺髓质素的测定
- Author:
Lihong RUAN
;
Yu PAN
;
Fengqua ZHU
- Publication Type:Journal Article
- Keywords:
Normal pregnancy;
Adrenomedullin;
RNA,messenger
- From:
Journal of Medical Postgraduates
2003;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the role of adrenomedullin(ADM) in normal early pregnancy. Methods: Plasma concentrations of ADM were measured in 30 normal early pregnancy and 10 non-pregnant women by radioimmunoassay. The expression of ADM?ADM mRNA and ADMR mRNA in villus of normal early pregnancy were determined by immunohistochemistry and in situ hybridization respectively. Results: The plasma concentration of ADM in normal early pregnancy was significantly higher than that of normal non-pregnant women (P