Study on the isolation of marine fungi , screening of their antitumor activity and fermentation conditions
- VernacularTitle:海洋真菌的分离、抗肿瘤活性筛选与发酵条件研究
- Author:
Chuiliang YU
;
Qianqun GU
;
Hongbing LIU
;
Yuchun FANG
;
Bing HAN
;
Bing CAI
- Publication Type:Journal Article
- Keywords:
marine microorganisms;
marine fungi;
cell cycling inhibiting;
cell apoptosis;
antitumor
- From:
Chinese Journal of Marine Drugs
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To isolate fungi from sea sediment and sea water samples collected from the neritic environment in Qingdao, screen their antitumor activity and study on their fermentation condition. Methods The antitumor activity was assayed by flow cytometry in mouse tsFT210 cells. Results The medium added penicillin and streptomycin possesses good selectivity. 207 strains of fungi were isolated and among them, 19 strains showed antitumor activity, and one fungus(Z 83200)pocesses strong cell apoptosis inducing activity.
