An experiment study on antitumor effect of Haishengsu injection
- VernacularTitle:海生素注射液抗肿瘤作用的实验研究
- Author:
Zhongxu LIU
;
Songmei ZHAN
;
Ruyong YAO
;
Lihua FANG
;
Xiu YANG
;
Chunbo WANG
- Publication Type:Journal Article
- Keywords:
haishengsu injection;
antitumor effect
- From:
Chinese Journal of Marine Drugs
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antitumor effect of Haishengsu injection extracted from marine shellfish. Methods Transplant tumor models of sarcoma 180 (S 180), Ehrlich ascites carcinoma (EAC), and hepatoma (Heps) in mice were established. Different doses of Haishengsu injection were given to the mice and the tumor inhibition rates of Haishengsu injection, life span of the mice were calculated. Results The tumor inhibition rates of haishengsu injection (490～1000mg?kg -1?d -1,iv) were 41.10%～49.08% in mice with S 180 and 36.29%～49.19% in mice with hepatoma,respectively. The same doses of Haishengsu injection prolonged the life spans of EAC-bearing mice by 22.93%～69.98%. Conclusion The haishengsu injection has the antitumor effects on the tumor-bearing mice without evident side effects.
