A modified animal model of orthotopic liver transplantation in rat
- VernacularTitle:改良“二袖套法”制备大鼠原位肝移植动物模型
- Author:
Jiageng ZHU
;
Lixin QIAN
;
Houguang HE
;
Wei ZHANG
- Publication Type:Journal Article
- Keywords:
Rat;
Liver transplantation;
Animal model
- From:
Journal of Medical Postgraduates
2003;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To make an ideal model for liver transplantation. Methods:On the basis of cuff technique,we carried out 62 cases of orthotopic liver transplantation in 3 months. In the transplantation,we anastomosed the portal vein and subhepatic vena cava with cuff and conneted the suprahepatic vena cava to the recipient's diaphragm with 9-0 running suture. Results:The average time of acquiring donor liver was 32 minutes, reqairing liver was 12 minutes,unhepatic phase was 18 minutes.62 liver transplantation operations were carried out ,in which the operation success rate in late 30 cases was 90%. Conclusion:The results show that the model is stable and can be used in the experiment of liver transplantation.
