Sentinel lymph node biopsy for forecasting axillary lymph node metastasis in breast cancer
- VernacularTitle:乳腺癌前哨淋巴结活检对腋窝淋巴结转移的预警价值研究
- Author:
Chunsen XU
;
Shunguo LIN
;
Hui HAN
- Publication Type:Journal Article
- Keywords:
Breast neoplasm;
Sentinel lymph node;
Lymphadenectomy;
Tumor metastasis
- From:
Chinese Journal of Minimally Invasive Surgery
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of sentinel lymph node (SLN) for forecasting axillary lymph node metastasis in breast cancer. Methods Fifty-six patients with breast cancer underwent SLN methylene blue mapping and biopsy,as well as axillary lymph node dissection.All lymph nodes received routine HE staining and immunohistochemical examination. Results SLN was successfully identified in 52 cases (52/56,92.8%).Routine pathological examination demonstrated metastasis of SLN in 22 cases and metastasis of non-SLN in 1 case,the false negative rate being 4 3% (1/23).In the remaining 29 cases without pathologically verified metastasis,immunohistochemical staining showed 1 case of CK-19 (+) with EMA (+) and another 1 case of CK-19 (+) with CEA (+),without metastasis of non-SLN. Conclusions SLN methylene blue mapping and biopsy may forecast axillary lymph node metastasis in breast cancer.
