A substype analyse of peripheral blood CDS lymphocyte in patients with chronic hepatitis virus B
- VernacularTitle:慢性乙型肝炎患者外周血CD8淋巴细胞的亚型分析
- Author:
Xianjun WANG
;
Wenjun JIN
;
Jun GE
;
Weihua ZOU
;
Jianfang HE
- Publication Type:Journal Article
- Keywords:
Hepatitis B ,chronic;
Flow cytometry;
CDS
- From:
Chinese Journal of Laboratory Medicine
2003;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the relationship between the substype of peripheral blood CD8 lymphocyte in patients with chronic hepatitis virus B and clinic condition and the replication of HBV. Methods CD45RO, CD45RA and CD28 of peripheral blood CD8 lymphocyte were detected by flow cytometry with multicolor fluorescence technology in 107 patients with chronic hepatitis virus B and 20 healthy volunteers. Results The total quantity of CD8 lymphocyte in patientswith chronic hepatitis virus B was not different from that in controls. The percent of CD3+ CD8+/CD45R0+ cells in patients with chronic active hepatitis was significantly higher than that of the control (15.7?3. 35)% vs( 8. 56?1. 12)% , P
