Frequency, risk factors and prognosis of stent thrombosis after primary percutaneous coronary intervention
- VernacularTitle:直接冠状动脉介入治疗支架内血栓形成的发生率、危险因素及预后
- Author:
Hongbing YAN
;
Jingshang LIU
;
Jian ZHANG
- Publication Type:Journal Article
- Keywords:
Acute myocardial infarction;
Percutaneous coronary intervention;
Primary, thrombosis
- From:
Chinese Journal of Interventional Cardiology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse frequency, risk factors and prognosis of stent thrombosis after primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI) during the last five-year period. Methods Primary PCI was performed in 311 patients with STEMI including 250 males and 61 females with an average age of 60.4 years (26～85 years). The standard triple antiplatelet/anticoagulation therapy with aspirin and clopidogreal plus heparin was used pre- and post-interventional procedure. All patients underwent more than two months follow-up investigation. Results A successful primary PCI procedure was achieved in 99% (308/311) STEMI patients with incidence of total stent thrombosis in 2.6% (8/308), including acute stent thrombosis in five patients and subacute or late thrombosis in three patients. Multiple risk factors could be identified in all the eight patients, of whom, three died of acute closure events and the follow-up study in the other five showed severe systolic dysfunction of left ventricle. Conclusion High incidence of stent thrombosis occurred after primary PCI for STEMI with high mortality and poor clinical prognosis. Application of small diameter and/or long stents and discontinuation of clopidogreal seem to be major risk factors.
