Using cardiac MRI to assess the myocardium necrosis of patients with acute coronary syndrome
- VernacularTitle:心脏磁共振影像评价急性冠状动脉综合征患者心肌损害的研究
- Author:
Jian LIU
;
Yi WANG
;
Weimin WANG
- Publication Type:Journal Article
- Keywords:
Acute coronary syndrome;
MRI;
Multi-coronary artery stenosis
- From:
Chinese Journal of Interventional Cardiology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the irreversible ischemia injury in patients with acute coronary syndrome using Cardiac MRI. Methods We have studied 35 patients with acute coronary syndromes who received standard medical therapy. Coronary angiogram confirmed that all the patients had suffered from multi-coronary artery stenosis without total occlusion. Cardiac MRI (CMRI) examinations were performed 6-12 weeks after the coronary angiography and revascularization. IR-GRE was used in the CMRI protocal to detect myocardial delayed enhancement (viability). The definition of hyperenhancement was that the signal of the region was two times that of the remote myocardium. The hyper-enhanced volume was presented as a percentage of LV mass (%LV), i.e. The total number of hyperenhanced pixels divided by the total number of pixels of the LV myocardium and multiplied by 100. Results CMRI revealed that all the patients had hyperenhanced region, of whom 30 (85.7%) had non-transmural enhancement and only 5 (14.3%) had transmural enhancement. The average size of the enhancement of non-transmural was significantly smaller than that of transmural hyperenhancement (45.7?7.3%). Conclusion The CMRI can demonstrate that infarction has occurred in patients with multi-coronary arteries stenosis.