Mirtazapine and Amitriptyline in the Maintenance Treatment of Depressed Patients:Comparison of Efficacy and Compliance
- VernacularTitle:米氮平和阿米替林维持治疗抑郁症患者的疗效和依从性比较
- Author:
Guohan YU
;
Guoan DING
;
Xuan LI
- Publication Type:Journal Article
- Keywords:
Mirtazapine Armitriptyline Depression Efficacy Compliance
- From:
Chinese Mental Health Journal
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the compliance and efficacy of mirtazapine or armitriptyline in the maintance treatment of depression. Methods:60 depressive outpatients were randomly allocated to two groups treated with mirtazapine or armitriptyline for 52 weeks. Before treatment and at the ends of 12 weeks and 52 weeks of treatment, to assess the efficacy using the Hamiltion Depression Scale (HAMD)and Clinical Global Impression(CGI),to assess the compliance and the adverse-effects using the Hamilton Depression Scale (HAMD)and Clinical Global Impression(CGI),to assess the compliance and the adverse-effects using Treatment Emergent Symptom Scale (TESS).Results:After 12 weeks, significant improvement was observed respectively in the two groups(P
