Preliminary matching of human leukocyte antigen multi-sites determination in single-cell
- VernacularTitle:单细胞人白细胞抗原多基因位点检测的配型预选性研究及意义
- Author:
Xiujun HAN
;
Fan JIN
;
Hefeng HUANG
;
Lixing YAN
- Publication Type:Journal Article
- Keywords:
Human leukocyte antigen;
Polymerase chain reaction;
Cord blood stem cell transplantation;
Preimplantation diagnosis
- From:
Chinese Journal of Laboratory Medicine
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusion The technique of PEP-MN-PCR from single-cell for simultaneous detection of HLA-A, B, DR types were efficient and accurate. It was possible to apply the techniques of PEP-MN-PCR to detect HLA-A, B, DR typing for preimplantational diagnosis, preliminary selection of HLA matching embryos and the patient sibling who needs cord blood stem cell transplantation.