The change and clinical significance of serum tumor necrosis factor-?、interleukin-6 and interleukin-8 after cutting balloon angioplasty and stent implantation
- VernacularTitle:切割球囊血管成形术加支架术后血清TNF-?和IL-6、IL-8的变化及其意义
- Author:
Xingwei ZHANG
;
Peizhang LI
;
Liang ZHOU
- Publication Type:Journal Article
- Keywords:
Cutting balloon angioplasty;
TNF ?;
Interleukin;
Restenosis
- From:
Chinese Journal of Interventional Cardiology
1993;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of cutting balloon angioplasty and stent implantation on serum TNF ?, IL 6 and IL 8, and investigate the relationship between the concentrations of serum TNF ?, IL 6 and IL 8 after operation and the incidences of late cardiac events after intervention Methods Eighty patients underwent PTCA with normal balloon or cutting balloon Values of serum TNF ?, IL 6 and IL 8 before and after intervention were measured using enzyme linked immuno sorbent assay Results The concentrations of serum TNF ?, IL 6 and IL 8 were increased significantly in the restenosis group, especially in the POBA group There was no obvious difference in no restenosis group Conclusion The lower restenosis rate in cutting balloon group was related to its lower injury and inflammation of blood vessels The concentrations of serum TNF ?, IL 6 and IL 8 6 hours after intervention may be the predictable sign of restenosis after intervention
