Expression of G protein inwardly rectifier potassium channels subunit 2 mRNA in hippocampus of temporal epileptic rat
- VernacularTitle:G蛋白偶联内向整流钾通道亚基2mRNA在颞叶癫大鼠海马内的表达
- Author:
Yu WANG
;
Bo XIAO
;
Xiaosu YANG
- Publication Type:Journal Article
- Keywords:
Epilepsy G protein inwardly rectifier potassium channels Hippocampus
- From:
Journal of Clinical Neurology
1988;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of G protein inwardly rectifier potassium channels subunit 2(GIRK*!2) in hippocampus of temporal epileptic rat.Methods After temporal lobe epilepsy was induced by kainic acid (KA), we took advantage of in situ hybridization to investigate the altered expression of GIRK*!2 mRNA in rat hippocampus.Results GIRK*!2 mRNA significantly increased in epileptic rats dentate gyrus region compared with normal control( P
