Effects of IL-2 on the proliferation activity and HCG secretion of human trophoblastic cells
- VernacularTitle:IL-2对人滋养层细胞的增殖活性和HCG分泌的影响
- Author:
Qi SUN
;
Yongxiu YANG
- Publication Type:Journal Article
- Keywords:
IL-2;
Trophoblastic cell;
Proliferation;
Secretion;
Pathologic pregnancy
- From:
Journal of Medical Postgraduates
2003;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effects of IL-2 on the proliferation activity and HCG secretion of first trimester human trophoblastic cells in vitro. Methods:Growing -well 4th generation trophoblastic cells were selected,cultured for 48 h with IL-2 of different concentration. The MTT colorimetric assay was used to analyze the proliferation activity, and radioimmunoassay was used to analyze the secretion of HCG. Results:①Low concentration (100 U/ml,400 U/ml) IL-2 promoted proliferation activity and HCG secretion (P