Comparison of zhibituo and lovastatin in the treatment of hyperlipidemia
- VernacularTitle:脂必妥与洛伐他汀用于治疗高胆固醇血症的对比分析
- Author:
Qiaoyun CHEN
;
Shuiyi WEI
;
Xiaoh LU
- Publication Type:Journal Article
- Keywords:
Zhibituo;
Lovastatin;
Drug evaluation
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the efficacy, safety and economics of zhibituo and lovastatin in the treatment of hyperlipidemia. Methods:Searching medical references were done, The qualified results of clinical trials were Meta-analysed for evaluating the efficacy of zhibituo comparing with lovastatin. The characters of zhibituo and lovastatin were also compared through scoring by senior physicians. Results:The results of Meta-analysis showed that zhibituo had stronger effects on lowering TG and elevating HDL.It had less severe ADR for old people and cost less than lovastatin. The results of physicians-scoring records showed no significant difference between these two drugs. Conclusion:Zhibituo and lovastatin both are potential lipid-lowering agents. zhibituo is safer and more cost-effective for old people with mild to moderate elevated serum LDL level.
