Effect of fetal transplants on functional recovery after spinal cord transecti on in newborn and adult rats
- VernacularTitle:新生鼠和成年鼠脊髓损伤后胚胎脊髓移植对大鼠损伤脊髓功能恢复的影响
- Author:
Qiang ZHANG
;
Lianshun JIA
- Publication Type:Journal Article
- Keywords:
Spinal cord injury;
Intraspinal graft;
Fetal spinal cor d;
Rats
- From:
Chinese Journal of Orthopaedic Trauma
2002;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of fetal transplants on the fu nctional recovery after spinal cord transection in new born and adult rats. Meth ods The spinal cord tissue at E14 of a rat fetal was transferred into the hemise ction cavity at lumbar spinal cord in the newborn and adult rats. 4, 8, 12 weeks after the operation, spinal cord tissue morphology, combined behavioral score ( CBS), somatosensory evoked potentials (SEP), and motor evoked potentials (MEP) w ere examined. Results The transplanted tissue survived in the host spinal cord. There was a statistical difference in CBS between the newborn graft group and th e adult graft group. The peak latencies of early waves in SEPs and MEPs of the n ewborn graft group were superior to those of the adult graft group (P
