Meta-analysis of 342 Female Pseudohermaphroditism
- VernacularTitle:342例女性假两性畸形的荟萃分析
- Author:
Quanrong LI
;
Bei UN
;
Xiling YI
;
Shuice LIU
;
Shengtan WANG
;
Shulan ZHANG
- Publication Type:Journal Article
- Keywords:
female pseudohermaphroditism;
meta-analysis
- From:
Journal of China Medical University
2010;(1):64-66,70
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the clinical characteristics of female pseudohermaphroditism (FPH) in the publication from 1994 to 2009 and the cases diagnosed and treated in our hospital from 2000.Methods We employed Chinese and English name of female pseudohermaphroditism as a key word separately to retrieve published articles of FPH during 1994 to 2009.A meta-analysis was performed together with the ten cases in our hospital.Results Among 342 cases involved in this study,only twenty-seven children were diagnosed immediately after birth and the other 315 cases at the age of 1 month to 59 years with median age of 29.54 years.The etiological factors were mostly congenital adrenal hyperplasia (70.47%).Clinical manifestations were advanced bone age (95.52%),clitoromegaly (84.14%) and early virilization (77.24%).The treatment mainly included drug and operation.Early diagnosis and available therapy were very important for the prognosis.Conclusion FPH is not rare,so we should improve our knowledge for its early diagnosis,good intervention and final better prognosis.
