Lipoprotein (a) and its immune complexes concentrations in patients with various dyslipidaemias
- VernacularTitle:高脂血症患者血清脂蛋白(a)及其特异性循环免疫复合物水平
- Author:
Daning CHEN
;
Junjun WANG
;
Chunni ZHANG
- Publication Type:Journal Article
- Keywords:
Lipoprotein(a);
Lower density lipoprotein;
Immune complexes;
Triglyceride;
Dyslipidaemias
- From:
Journal of Medical Postgraduates
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the possible interaction of Lp(a), and Lp(a) circulating immune complexes (CIC) 〔Lp(a)-CIC〕 level with triglyceride (TG). Methods:Plasma Lp(a), Lp(a)-CIC and LDL-CIC levels were determined by ELISAs in 232 patients with various dyslipidaemias, respectively. Results:Hypertriglyceridaemic patients exhibited the lowest plasma Lp(a) levels, while hypercholesterolaemic patients exhibited the highest. Patients with mixed hyperlipidaemia had intermediate serum Lp(a) concentrations, which were significantly lower than those in the controls. Interestingly, we also found that hypertriglyceridaemic patients exhibited the lowest plasma Lp(a)-CIC and LDL-CIC levels, while hypercholesterolaemic patients exhibited the highest. TG levels were negatively correlated with Lp(a) (r=-0.15, P
