Expressions of NOS2 and NOS3 in human non-small cell lung cancer and the relationship with tumor angiogenesis and lymph node metastasis
- VernacularTitle:一氧化氮合酶2、3在非小细胞肺癌中的表达及其临床意义
- Author:
Jinghua WANG
;
Longbang CHEN
;
Henghui MA
;
Ku MENG
- Publication Type:Journal Article
- Keywords:
NOS2;
NOS3;
Non-small cell lung cancer;
Lymph node metastasis
- From:
Journal of Medical Postgraduates
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the expression and distribution of NOS2 and NOS3 in human non-small cell lung cancer (NSCLC),and to evaluate the relationship between their expression and tumor angiogenesis and lymph node metastasis. Methods: the expression of NOS2, NOS3 and IMVD in 95 patients with NSCLC were examined using immunohistochemical methods (S-P), and the relationship between them and many clinicopathological parameters was analyzed. Results: The positive expression of NOS3 was associated with histological subtype, IMVD and lymph node metastases of NSCLC(P
