Primary clinical application of MR diffusion tensor imaging in diagnosis of central nervous system diseases
- VernacularTitle:磁共振弥散张量成像在诊断中枢神经系统疾病的初步应用
- Author:
Ning CHEN
;
Zongyao CAI
;
Wen LIU
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging Diffusion tensor imaging
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinic role of diffusion tensor imaging in diagnosis of central nervous system diseases with damage of white matter fibro bands.Methods Ten healthy volunteers and sixty-four patients(31 cases of cerebral vascular disease, 7 cases of demyelinating disease, 7 cases of inflammatory disease, 10 cases of tumor, 2 cases of degenerative disease, 2 cases of congenital brain dysgenesis, 3 cases of brain atrophy, and 2 cases of others) underwent MRI examination, which included conventional T 1WI, T 2WI, T 2 Flair and diffusion tensor. Fractional anisotropy(FA) were measured in white matter tracts and gray matter.Results Ablation of white matter fibro tracts and reduction of FA could be found in 59 patients(92.1%).Erosion like alteration was seen in 12 patients(20.3%).In all the patients with tumors showed push and displacement of the white matter fibro tracts.Conclusion Diffusion tensor imaging can show lesions in white matter at early stage of some diseases.It is better in displaying damage or displacement of white matter tracts than conventional MRI.
