Application of dynamic contrast-enhanced perfusion MR imaging in intracranial tumors
- VernacularTitle:动态对比增强灌注磁共振成像在颅脑肿瘤的应用
- Author:
Xueman JI
;
Honglin WU
;
Guangming LU
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging;
Perfusion;
Cerebral tumor;
Cerebral blood volume
- From:
Journal of Medical Postgraduates
2004;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Dynamic contrasted-enhanced perfusion MR imaging can provide noninvasive and physical maps of cerebral microcirculation. The tumor vascularities are assessed by calculating cerebral blood volumes of the normal cerebral tissue and tumor tissue from imaging signal intensities. This technique is helpful to better evaluate the histopathological grade of gliomas, determine the biopsy site for tumors. And it is very useful for the preoperative diagnosis of gliomas, solitary metastases, cerebral lymphomas, as well as differentiating tumor recurrence after surgical resection and radiotherapy from radiation necrosis. But there are some limitations in evaluating extraaxial tumors and cerebral tumors with severe breakdown of blood-brain barrier.