Studies on the method of calculating deferral periods of blood donors after taking traditional Chinese medicines
- VernacularTitle:献血者服用中药后延期献血期限设定的探讨
- Author:
Yi HE
;
Xuehua JIANG
;
Ping LUO
- Publication Type:Journal Article
- Keywords:
Drug safety,Blood donors,Traditional Chinese medicine
- From:
Chinese Journal of Blood Transfusion
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for calculating deferral periods of blood donors having taken traditional Chinese medicines based on the drug's pharmacokinetics.Methods The pharmacokinetic method was used.For drugs that are not known to cause anaphylaxis or teratogenesis,the interval between last dose of drug and safe blood donation equals to t max plus 7t 1/2 .For drugs with known teratogenic and anaphylactic risks,a deferral period of 20 plasma elimination half lives and t maxis necessary.There are some rules independent of the drug's half life.Results 22 intervals of traditional Chinese medicine are determined.Conclusion Our recommendations for deferral periods of blood donors after traditional Chinese medicine treatment,based on pharmacokinetics can increase the safety of donated blood.
