Understanding of Human Embryo Development for Teratogen Counselling.
- Author:
Yikyeong CHUN
1
;
Heechul LEE
Author Information
1. Department of Pathology, Cheil General Hospital and Women's Healthcare Center, Dankook University School of Medicine, Seoul, Korea.
- Publication Type:Review
- Keywords:
embryology;
neural crest;
congenital abnormalities;
gastrulation;
neurulation
- MeSH:
Congenital Abnormalities;
Ectoderm;
Embryology;
Embryonic Development*;
Embryonic Structures*;
Endoderm;
Female;
Gastrulation;
Germ Layers;
Human Development;
Humans*;
Mesoderm;
Mothers;
Neural Crest;
Neurulation;
Parturition;
Pregnancy;
Teratogens
- From:Journal of the Korean Society of Maternal and Child Health
2016;20(2):112-118
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Human embryology is the study of development from a single cell to a baby in 9 months. Implantation occurs at the end of the first week of development. The second week of development is known as the week of 2's. Gastrulation, the most characteristic event occurring in the third week, establishes three germ layers composed of ectoderm, mesoderm, and endoderm. The three germ layers and neural crest cells lead to the development of their own tissues and organs during the embryonic period, which extends from the third to the eighth week. Major congenital malformations occur in the embryonic period. The fetal period, from the third month to the day of birth, is the time for maturation of tissues and organs, and growth of the body. Because of the close relationship between embryology and congenital abnormalities, knowledge of human development is essential to assess the effects on the embryo when the mother has been exposed to teratogens. This paper briefly reviews the normal embryonic development and associated congenital malformation.
