Content Change of CollagenⅠ, Ⅲ in Liver and Spleen of Patients with Advanced Schistosomiasis Japonica
- VernacularTitle:晚期血吸虫病患者肝脾Ⅰ、Ⅲ型胶原含量的变化
- Author:
Jialin CHEN
;
Jun TAO
;
Weimin CAI
;
Yanping ZHANG
- Publication Type:Journal Article
- Keywords:
schistosomiasis japonica, liver, spleen, collagen type I, collagen type Ⅲ
- From:
Chinese Journal of Parasitology and Parasitic Diseases
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change of the content of collagen typeⅠand collagen type Ⅲ (C-Ⅰ, C-Ⅲ) in liver and spleen of patients with advanced schistosomiasis japonica. Methods Sirius red staining was used to examine pathologically the liver and spleen biopsy materials from 55 patients at the advanced stage of schistosomiasis and 5 healthy persons as control. The stained slides were observed under polarizing microscope and results were interpreted by computer imaging analysis system. (Results) The content of C-Ⅰand C-Ⅲ in liver tissue and hepatic sinusoids increased significantly in the patients than that of the control (P
