The clinical progress of antisense technology in the treatment of cancer
- VernacularTitle:反义技术治疗肿瘤的临床进展
- Author:
Wei YAN
;
Gang FANG
- Publication Type:Journal Article
- Keywords:
Antisense technology;
Cancer;
Clinical progress
- From:
Journal of Medical Postgraduates
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
According to the base complementation, the principle antisense technology is the sequence specific binding of complementary antisense nucleic acids or their chemical modification to the nucleic acids in cells, resulting in the suppression or prevention of gene translation. For the treatment of cancer, a lot of antisense drugs have been designed, which target the genes involved in the pathogenesis of cancer. And some of them have been in clinical trials. The author reviewed the progress of the clinical trials of these antisense drugs.
